Package: vrnmf 1.0.2

Evan Biederstedt

vrnmf: Volume-Regularized Structured Matrix Factorization

Implements a set of routines to perform structured matrix factorization with minimum volume constraints. The NMF procedure decomposes a matrix X into a product C * D. Given conditions such that the matrix C is non-negative and has sufficiently spread columns, then volume minimization of a matrix D delivers a correct and unique, up to a scale and permutation, solution (C, D). This package provides both an implementation of volume-regularized NMF and "anchor-free" NMF, whereby the standard NMF problem is reformulated in the covariance domain. This algorithm was applied in Vladimir B. Seplyarskiy Ruslan A. Soldatov, et al. "Population sequencing data reveal a compendium of mutational processes in the human germ line". Science, 12 Aug 2021. <doi:10.1126/science.aba7408>. This package interacts with data available through the 'simulatedNMF' package, which is available in a 'drat' repository. To access this data package, see the instructions at <https://github.com/kharchenkolab/vrnmf>. The size of the 'simulatedNMF' package is approximately 8 MB.

Authors:Ruslan Soldatov [aut], Peter Kharchenko [aut], Viktor Petukhov [aut], Evan Biederstedt [cre, aut]

vrnmf_1.0.2.tar.gz
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vrnmf.pdf |vrnmf.html
vrnmf/json (API)

# Install 'vrnmf' in R:
install.packages('vrnmf', repos = c('https://kharchenkolab.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/kharchenkolab/vrnmf/issues

On CRAN:

13 exports 17 stars 2.01 score 6 dependencies 12 scripts 269 downloads

Last updated 2 years agofrom:968a29edda. Checks:OK: 7. Indexed: yes.

TargetResultDate
Doc / VignettesOKSep 03 2024
R-4.5-winOKSep 03 2024
R-4.5-linuxOKSep 03 2024
R-4.4-winOKSep 03 2024
R-4.4-macOKSep 03 2024
R-4.3-winOKSep 03 2024
R-4.3-macOKSep 03 2024

Exports:AnchorFreefactor_intensitiesinfer_intensitiesprojection_onto_simplexsim_factorsvol_preprocessvolnmf_detvolnmf_estimatevolnmf_logdetvolnmf_mainvolnmf_procrustesvolnmf_simplex_colvolnmf_simplex_row

Dependencies:icalatticelpSolveAPIMatrixnnlsquadprog