{ "_id": "6a37ad1a3efcd9bda4424e33", "Package": "vrnmf", "Title": "Volume-Regularized Structured Matrix Factorization", "Version": "1.0.2", "Authors@R": "c(person(\"Ruslan\", \"Soldatov\", email = \"ruslansoldatov@gmail.com\", role = c(\"aut\")), person(\"Peter\", \"Kharchenko\", email = \"peter_kharchenko@hms.harvard.edu\", role = \"aut\"), person(\"Viktor\", \"Petukhov\", email = \"viktor.s.petukhov@ya.ru\", role = c(\"aut\")), person(\"Evan\", \"Biederstedt\", email=\"evan.biederstedt@gmail.com\", role=c(\"cre\", \"aut\")))", "Description": "Implements a set of routines to perform structured matrix\nfactorization with minimum volume constraints. The NMF\nprocedure decomposes a matrix X into a product C * D. Given\nconditions such that the matrix C is non-negative and has\nsufficiently spread columns, then volume minimization of a\nmatrix D delivers a correct and unique, up to a scale and\npermutation, solution (C, D). This package provides both an\nimplementation of volume-regularized NMF and \"anchor-free\" NMF,\nwhereby the standard NMF problem is reformulated in the\ncovariance domain. This algorithm was applied in Vladimir B.\nSeplyarskiy Ruslan A. Soldatov, et al. \"Population sequencing\ndata reveal a compendium of mutational processes in the human\ngerm line\". Science, 12 Aug 2021.\n. This package interacts with data\navailable through the 'simulatedNMF' package, which is\navailable in a 'drat' repository. To access this data package,\nsee the instructions at\n. The size of the\n'simulatedNMF' package is approximately 8 MB.", "License": "GPL-3", "Encoding": "UTF-8", "RoxygenNote": "7.1.2", "URL": "https://github.com/kharchenkolab/vrnmf", "BugReports": "https://github.com/kharchenkolab/vrnmf/issues", "Author": "Ruslan Soldatov [aut], Peter Kharchenko [aut], Viktor Petukhov\n[aut], Evan Biederstedt [cre, aut]", "Maintainer": "Evan Biederstedt ", "Repository": "https://kharchenkolab.r-universe.dev", "Date/Publication": "2022-04-14 14:35:05 UTC", "RemoteUrl": "https://github.com/kharchenkolab/vrnmf", "RemoteRef": "HEAD", "RemoteSha": "968a29eddad04b92cee7b8067b504082b31d53f8", "NeedsCompilation": "no", "Packaged": { "Date": "2026-06-21 09:18:42 UTC", "User": "root" }, "MD5sum": "7f7c9e95bf62c76b0185a0a3b832834f", "_user": "kharchenkolab", "_type": "src", "_file": "vrnmf_1.0.2.tar.gz", "_fileid": "948a55a0464af413b374b56e17a9256e6311b72854466a935a8a355f435cc887", "_filesize": 177766, "_sha256": 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